MedMisti™

When breathing is hard,
treatment should feel easier.

A wearable, breath actuated smart inhalation system designed to make respiratory treatment easier to use, easier to track and better aligned to real breathing behaviour.
Overview

A wearable mask designed
around the breath.

MedMISTI brings MISTI’s pulmonary delivery technology into a wearable mask system designed for respiratory care.

It is built to detect inhalation, generate a fine mist and capture treatment information, helping make inhaled therapy easier for patients and more visible for caregivers and care teams.

The MedMISTI mask system brings together:

A pre filled liquid cartridge

A reusable wearable mask

A connected digital layer

A breath actuated transducer

In simple terms, MedMISTI is designed to do three things well:

  • Deliver medicine when the patient inhales.
  • Reduce the coordination burden of traditional devices.
  • Capture treatment information that can support better care visibility.

This is where the MISTI delivery approach becomes practical: not as a technical idea, but as a treatment experience designed around real patients.

Problem it Solves

Respiratory treatment should not be harder when breathing already is.

Many inhaled therapies rely on the patient doing everything correctly.

  • Breathe at the right time.
  • Use the device properly.
  • Tolerate the mask or spacer.
  • Complete the dose.
  • Repeat the process consistently.

For many patients, the issue is not willingness. It is usability.

  • A child may resist a spacer because it feels frightening.
  • An elderly patient may mistime or forget treatment.
  • A caregiver may be unsure whether the full dose was completed.
  • A clinician may have little visibility over what happened at home.

MedMisti™ is being developed to address the treatment moment itself.

The aim is to make inhaled therapy more usable, more visible and more closely aligned with the patient’s natural breathing behaviour.

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How MedMisti™ Works

Designed to wait for the breath,
then deliver.

MedMisti™ is designed to align medicine delivery with inhalation.
Rather than relying on the patient to coordinate perfectly with the device, the system
detects when the patient begins to breathe in and activates aerosol generation in
response.

How the process works:

The cartridge is prepared

A pre filled liquid cartridge holds the prescribed medicine with minimal handling.

The mask is
fitted

The wearable mask supports hands free delivery and helps reduce coordination demands.

The breath is detected

The system identifies when the patient begins to inhale.

The mist is
generated

The mesh free acoustic transducer turns liquid into a fine breathable aerosol.

The treatment event is captured

Connected use data can support adherence tracking and care visibility.

Mask in Action

What using MedMisti™ could feel like.

The patient wears the mask.

The system waits for the inhale.

Medicine is turned into a fine mist.

Treatment is delivered without the same coordination demands as traditional inhalers, spacers or nebulisers.

Use data is captured to support visibility for caregivers and care teams.

This is the practical value of MedMisti™: the treatment experience is designed to work with the patient, not against them.

Real World Use

Built for real patients, not perfect conditions.

Respiratory treatment does not always happen in calm, controlled clinical environments.

It happens at home. After discharge. In aged care. During flare ups. Under caregiver support. With children who are frightened, elderly patients who need help, and people whose breathing is already compromised.

MedMisti may be relevant where patients struggle with traditional inhalers, spacers or nebulisers due to:

  • Low breathing strength
  • Coordination difficulty
  • Sensory sensitivities
  • Cognitive challenges
  • Treatment anxiety or resistance

The wearable, breath actuated format is intended to reduce the pressure on the patient to perform the treatment perfectly.

That matters because respiratory treatment only works when it can actually be completed.

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Usability and Patients

If patients cannot use it, treatment
cannot work as intended.

In respiratory care, usability is not a nice to have. If patients cannot tolerate, understand or complete treatment, the therapy cannot perform as intended.

MedMisti™ has undergone early end user testing through a pre pilot usability study at the University of Melbourne’s Digital Simulation Lab. The study involved 15 participants, including caregivers and children aged 8 to 14 years, and combined hands on device interaction with a guided app demonstration.

Feedback was strongly positive:

93%

Felt confident using the device at home

79%

Reported good comfort

79%

Found the main menu clear

92%

Preferred MedMisti™ to a spacer

64%

Rated ease of use as easy or very easy

The feedback also identified practical improvements around ergonomics, onboarding and in app labelling, helping guide the next stage of product refinement.

For patients and caregivers, this is the point: treatment should feel possible.

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Platform Connection

The first application of a broader platform.

MedMisti™ gives Misti® a focused starting point in respiratory care, where usability, timing and treatment visibility can directly affect outcomes.

The same principles behind MedMisti™, including breath actuated delivery, mesh free aerosol generation, connected treatment visibility and patient centred design, may support future pathways across advanced therapeutics and broader pulmonary delivery applications. 

This keeps MedMisti™ grounded in respiratory care while showing the larger purpose behind the technology.

Designed as a first step, not a final stop.

MedMisti starts in respiratory care, but the delivery principles behind it may support future applications across advanced inhaled therapeutics, connected respiratory monitoring, pharmaceutical co-development and public health deployment.

Its role is to prove the delivery approach in a real world respiratory care setting, then help inform what may come next.

The first mask opens the pathway for a wider generation of pulmonary delivery solutions designed around breath, usability and treatment visibility.

Two students in lab coats, one attentively listening and the other smiling, engage with a teacher in a science lab. A microscope and periodic table are visible.

See MedMisti™ in action.

MedMisti™ shows how Misti’s pulmonary delivery platform becomes visible, wearable and practical. Explore how the mask works, how it supports respiratory care and how it may open future
pathways for connected inhaled therapy.

Questions

Find answers about how MedMisti™ works and what it can do for you

1. What is the MedMisti™ mask?

MedMisti is a wearable smart inhalation mask that uses breath actuated, mesh free aerosol generation to help deliver medicine through the lungs while capturing connected treatment data.

MedMisti uses a pre filled liquid cartridge, wearable mask, breath sensing technology and a mesh free acoustic transducer. The system is designed to detect inhalation, generate a fine aerosol and capture connected treatment data during use.

MedMisti is being developed for patients who may need inhaled therapy to be easier and more consistent, including children, elderly patients, neurodiverse patients, people living with asthma or COPD, and people with compromised respiratory capacity.

MedMisti is breath actuated, wearable, connected and mesh free. It is designed to align aerosol delivery with inhalation, reduce coordination demands and provide treatment visibility through connected use data.

Yes. MedMisti™ has undergone early pre pilot usability testing at the University of Melbourne’s Digital Simulation Lab with caregivers and children aged 8 to 14 years. Feedback included confidence using the device at home, reported comfort, clear app navigation and preference over spacer use.

MedMisti™ is progressing through early technical and user validation. It should not be presented as fully clinically validated at this stage. Further external validation, regulatory work, clinical testing and manufacturing readiness are still required.

MedMisti™ is designed to capture connected use events, breath detection, actuation timing, device use and delivery related information. This may support adherence tracking, remote monitoring and clinical review.

MedMisti™ is the first focused application of Misti’s pulmonary delivery technology. It applies the platform’s mesh free aerosol generation, breath actuated delivery, wearable usability and connected visibility in respiratory care, while supporting future expansion into advanced therapeutics and broader pulmonary delivery applications.

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Our team is ready to answer specific questions about your situation